What class is Wellbutrin for pregnancy?

Drug FDA pregnancy category*
Bupropion (Wellbutrin) B
Duloxetine (Cymbalta) C
Mirtazapine (Remeron) C
Nefazodone (Serzone)‡ C

Is Wellbutrin safe when pregnant?

Bupropion (Wellbutrin).

Although bupropion isn’t generally considered a first line treatment for depression during pregnancy, it might be an option for women who haven’t responded to other medications. Research suggests that taking bupropion during pregnancy might be associated with miscarriage or heart defects.

What does Category C mean for pregnancy?

Category C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Is Wellbutrin a Category B?

For example, bupropion, marketed as Wellbutrin for depression and Zyban for smoking cessation, has been classified as a category B compound based on anecdotal human data from a very small sample of women and limited animal data, which do not support adverse effects associated with prenatal exposure.

What class of drug is Wellbutrin?

WELLBUTRIN (bupropion hydrochloride), an antidepressant of the aminoketone class, is chemically unrelated to tricyclic, tetracyclic, selective serotonin re-uptake inhibitor, or other known antidepressant agents. Its structure closely resembles that of diethylpropion; it is related to phenylethylamines.

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Can Wellbutrin cause birth defects?

The largest of these studies included data from the Bupropion Pregnancy Registry which reported the outcomes of 675 pregnancies with first-trimester bupropion exposure. The rate of birth defects was 3.6%, which is comparable to rates observed in the general population rate.

What is the safest antidepressant for pregnancy?

Antidepressants that are considered safer include:

  • Fluoxetine (Prozac, Sarafem)
  • Citalopram (Celexa)
  • Sertraline (Zoloft)
  • Amitriptyline (Elavil)
  • Desipramine (Norpramin)
  • Nortriptyline (Pamelor)
  • Bupropion (Wellbutrin)

Which pregnancy category is the riskiest?

Category X: Studies in animals or human beings have demonstrated fetal abnormalities, or there is evidence of fetal risk. The drug is contraindicated in women who are or may become pregnant.

Are Class C drugs safe during pregnancy?

Category C

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

What is pregnancy risk category B?

Category B: Either animal-reproduction studies have not demonstrated a fetal risk but there are no controlled studies in pregnant women or animal-reproduction studies have shown an adverse effect (other than a decrease in fertility) that was not confirmed in controlled studies in women in the first trimester (and there …

Can Wellbutrin cause a miscarriage?

Can taking bupropion in pregnancy cause miscarriage? Only one small study has investigated risk of miscarriage. The results of this study, in which women were taking bupropion as an antidepressant, do not prove that bupropion use in pregnancy causes miscarriage.

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Can you breastfeed while on Wellbutrin?

Can I breastfeed while taking bupropion? Bupropion is found in breast milk. When a mother takes bupropion only a small amount reaches the baby (0.11% – 1.99%). Breastfeeding while taking bupropion should not be harmful for most babies.

Does Wellbutrin cross the placenta?

Conclusion. Bupropion and its active metabolites cross the placenta to the fetal circulation.