Quick Answer: Is acyclovir safe in third trimester?

Long-term suppressive therapy can significantly reduce these outbreaks and is likely safe during pregnancy. Acyclovir (Zovirax) and valacyclovir (Valtrex) are the drugs most commonly used for herpes outbreak suppression and treatment during pregnancy. These drugs help reduce how active the virus is.

Can I take acyclovir throughout pregnancy?

It’s usually safe to use the cream or take aciclovir during pregnancy. Speak to your doctor, who’ll be able to explain the benefits and the risks of taking aciclovir when pregnant. They can help you decide on the best treatment for you and your baby.

Can you take valacyclovir in third trimester?

Valacyclovir Pregnancy Warnings

Comments: -Acyclovir (aciclovir) has been safely used to treat genital herpes in women in all stages of pregnancy; data on prenatal exposure to this prodrug is limited, however, animal data suggests low risk.

What can acyclovir cause while being pregnant?

Acyclovir, an antiviral nucleoside analogue, is a widely used agent highly specific for herpes simplex and varicella-zoster viruses. Unintended exposure to acyclovir early in pregnancy, which is not uncommon, may cause excessive maternal and physician anxiety.

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Can you take acyclovir for 6 months?

We conclude that suppression by oral acyclovir of frequently recurrent genital herpes remains effective for at least six months.

Does acyclovir cause birth defects?

Conclusion: Use of acyclovir in the first trimester does not increase birth defects, and it should be the antiviral drug of choice in early pregnancy.

What should you not take with acyclovir?

Common medications that may interact with acyclovir include:

  • amphotericin.
  • clozapine.
  • hepatitis B medications, such as entecavir.
  • HIV medications, such as tenofovir and zidovudine.
  • gentamicin.
  • NSAIDs, such as ibuprofen, diclofenac, or naproxen.
  • other antivirals, such as valacyclovir.
  • probenecid.

Does acyclovir cross the placenta?

Acyclovir is known to cross the placenta to the fetus. Frenkel et al4 reported the specific pharmacokinetics of acyclovir in pregnant patients with recurrent HSV receiv ing either 200 or 400 mg of acyclovir orally every 8 hours from 38 weeks’ gestation until delivery.

Can you take antivirals while pregnant?

Taking antiviral medications can prevent serious flu complications, such as pneumonia. Although it’s important to be cautious with any medication during pregnancy, research suggests that the benefits outweigh the potential risks of antiviral medications to treat flu during pregnancy.

What category is acyclovir for pregnancy?

All formulations of acyclovir are assigned FDA pregnancy category C status ****, which indicates that safety in human pregnancies has not been determined; therefore, the drug should not be used during pregnancy unless the potential benefit justifies the potential risk to the fetus.

Is it bad to take acyclovir everyday?

After stopping treatment the frequency of recurrences (0.71 per 28 days) was significantly less than the pre-treatment period (p = 0.001). No important side-effects were seen. It is concluded that long-term suppression with acyclovir is safe and effective for patients with recurrent genital herpes.

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Is it OK to take acyclovir daily?

Typical dosage for prevention of recurrent herpes: 400 mg twice per day, every day for up to 12 months. Other dosing plans may include doses ranging from 200 mg three times daily to 200 mg five times daily. Your doctor will decide how long you should take this drug to avoid a flare-up of the infection.

Can you take acyclovir for life?

Nevertheless, we conclude that the use of oral acyclovir for more than 12 months provides substantial additional prevention against recurrence of ocular HSV. Our data suggest that long-term oral acyclovir use remains effective in decreasing the number of recurrences beyond 12 months.