Conclusions. Levothyroxine requirements increase as early as the fifth week of gestation. Given the importance of maternal euthyroidism for normal fetal cognitive development, we propose that women with hypothyroidism increase their levothyroxine dose by approximately 30 percent as soon as pregnancy is confirmed.
How much does levothyroxine increase during pregnancy?
It is recommended that hypothyroid women can increase levothyroxine dose by approximately 30% as pregnancy is confirmed (Alexander et al., 2004).
How much does TSH increase in pregnancy?
The Endocrine Society recommends that TSH levels be maintained between 0.2-<2.5 mU/L in the first trimester of pregnancy and between 0.3-3 mU/L in the remaining trimesters.
Why is levothyroxine increased during pregnancy?
Higher levels of thyroid hormone are needed during pregnancy and, in women with normal thyroid function, the thyroid gland increases the production of thyroid hormone to meet this increased need. In hypothyroid women, this often means that the dose of Levothyroxine needs to be increased during pregnancy.
Do I need to increase my levothyroxine when pregnant?
Levothyroxine and pregnancy
You’ll need to have regular blood tests during pregnancy to make sure you’re on the right dose of levothyroxine for you and your baby. Most women need to take a higher dose of levothyroxine than usual while they’re pregnant.
Can I still take my thyroid medicine while pregnant?
Yes, it’s safe. In fact, it’s unsafe not to take thyroid medication during pregnancy if you need it. Whether you have hypothyroidism (an underactive thyroid) or the much less common hyperthyroidism (an overactive thyroid), you’ll probably need to take medication and be closely monitored.
Is it safe to take thyroid medicine during pregnancy?
Levothyroxine is the most common medicine used to treat an underactive thyroid during pregnancy. Levothyroxine replaces the thyroid hormone T4, which your own thyroid isn’t making or isn’t making enough of. It’s safe to take this medicine during pregnancy.
Can I have a healthy baby with hypothyroidism?
Early studies found that children born to mothers with hypothyroidism during pregnancy had lower IQ and impaired psychomotor (mental and motor) development. If properly controlled, often by increasing the amount of thyroid hormone, women with hypothyroidism can have healthy, unaffected babies.
Does TSH rise in pregnancy?
Thyroid hormone has an important role in brain development of the baby during pregnancy. It is clear that overt hypothyroidism (increased TSH levels and low thyroid hormone levels) in the mother, especially early in pregnancy, can affect the baby’s brain development or cause other problems with the pregnancy.
How can I control my high thyroid during pregnancy?
Experts recommend only using levothyroxine (T4) while you’re pregnant. Some women with subclinical hypothyroidism—a mild form of the disease with no clear symptoms—may not need treatment. Your doctor may prescribe levothyroxine to treat your hypothyroidism.
When should I stop taking levothyroxine during pregnancy?
If pregnant women are treated with L-thyroxine for isolated maternal hypothyroxinaemia, they too can stop the drug after delivery. We suggest these women, who stop L-thyroxine after delivery, should have an assessment of thyroid function about 6 weeks after the delivery,” Dr. Vaidya added.
Can too much thyroxine cause miscarriage?
Researchers from the University of Chicago have showed, for the first time, that an excess of thyroid hormone during pregnancy has a direct toxic effect on the fetus, tripling the risk of miscarriage and reducing the average birth weight of infants who survive.
When should thyroid medication be taken during pregnancy?
T4 treatment should be increased by 4–6 weeks gestation and the increase in dosage may be of the order of 30–50%. If hypothyroidism is diagnosed in pregnancy the T4 dose should be titrated rapidly until a TSH of <2.6 mU/L is attained.