Zofran is approved for nausea and vomiting in chemo patients and in those recovering from surgery only. Regarding Zofran during pregnancy and the potential side effects Zofran is classified as a Pregnancy Class B drug. This definition means that Zofran has no data and no studies available to prove it is safe.
Is it safe to take Zofran while pregnant?
Zofran is approved by the Food and Drug Administration (FDA) for use to fight off nausea related to chemotherapy. It is not currently approved by the FDA for morning sickness. Even so, most studies show that ondansetron is safe to use during the first trimester when most women experience morning sickness.
What drug class does Zofran belong to?
Ondansetron is in a class of medications called serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin, a natural substance that may cause nausea and vomiting.
Does Zofran help with nausea in pregnancy?
Ondansetron (Zofran®) is a medicine used to treat nausea and vomiting that may be caused by surgery, chemotherapy, or radiation therapy. Healthcare professionals also prescribe ondansetron during pregnancy to reduce symptoms of nausea and vomiting, also known as “morning sickness.”
Is Zofran contraindicated in pregnancy?
It has been used off-label to treat nausea and vomiting in pregnancy. Based on recent studies regarding the association between Zofran use in early pregnancy and congenital cardiac malformations and oral clefts (cleft lip and palate), the FDA has cautioned against its use in pregnancy.
Does taking ondansetron increase the chance of birth defects? Every pregnancy starts out with a 3-5% chance of having a birth defect. This is called the background risk. Most studies have found no increased chance for birth defects among thousands of people who used ondansetron in the first trimester of pregnancy.
What nausea medicine is safe while pregnant?
In fact, the FDA has approved a prescription medication for use during pregnancy that is a combination of Vitamin B6 and Unisom. It is called Diclegis. This is the only FDA approved medication for treating nausea and vomiting during pregnancy.
Is Zofran a narcotic?
Is Zofran (ondansetron) a narcotic? No, Zofran (ondansetron) is not a narcotic, instead it belongs to a class of medication called 5-HT3 (serotonin) receptor antagonist.
Is too much Zofran bad?
What happens if I overdose on Ondansetron (Zofran)? Overdose symptoms may include sudden loss of vision, severe constipation, feeling light-headed, or fainting.
What is the strongest anti nausea medication?
Motion (travel) sickness: hyoscine is the most effective medicine for motion sickness. Promethazine, cyclizine, or cinnarizine also work well.
Is ondansetron safe in first trimester of pregnancy?
Ondansetron. Although ondansetron has limited safety data in pregnancy, it is often prescribed for women with hyperemesis gravidarum. It is not recommended as first-line therapy, especially in the first trimester of pregnancy. Ondansetron commonly causes constipation, which may already be a problem in pregnancy.
How often can I take Zofran 4 mg for nausea?
The 4-mg dose is taken again 4 and 8 hours after the first dose. Then, the dose is 4 mg every 8 hours for 1 to 2 days. Children younger than 4 years of age—Use and dose must be determined by your doctor.
How long does it take for Zofran to work for morning sickness?
Ondansetron is an anti-sickness medicine. It will start to work within 1-2 hours.